Save this to
Documents\The Lord of the Rings Online\ui\skins\HideVitals\SkinDefinition.xml or add the two panel parts to your current skin.
Code:
<?xml version="1.0" encoding="UTF-8"?>
<opt>
<SkinName Name="Hide Vitals" />
<PanelFile ID="ID_UISkin_AvatarPanel">
<Element ID="AvatarPanel">
<Element ID="VitalsParent" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="HiddenDragBox_DragBox" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="HiddenDragBox_DragBar" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="HiddenDragBox_TitleText" X="-10000" Y="0" Width="1" Height="1"/>
</Element>
</PanelFile>
<PanelFile ID="ID_UISkin_OpponentPanel">
<Element ID="OpponentPanel">
<Element ID="LockOnOverlay" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="VitalsParent" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="HiddenDragBox_DragBox" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="HiddenDragBox_DragBar" X="-10000" Y="0" Width="1" Height="1"/>
<Element ID="HiddenDragBox_TitleText" X="-10000" Y="0" Width="1" Height="1"/>
</Element>
</PanelFile>
</opt>